Issue 34, 2005
From the journal:

Chemical Communications

Aptamer biosensor for label-free impedance spectroscopy detection of proteins based on recognition-induced switching of the surface charge†

Marcela C. Rodriguez,a   Abdel-Nasser Kawdea  and  Joseph Wang*a  

* Corresponding authors

a Departments of Chemical and Material Engineering and Chemistry and Biochemistry, The Biodesign Institute, Arizona State University, Tempe, USA
E-mail: joseph.wang@asu.edu
Tel: 1-480-727-0399

Abstract

The recognition of proteins by aptamer-modified electrode transducers reverses the surface charge and leads to a novel label-free impedance spectroscopy bioelectronic detection protocol based on a decrease in the electron transfer resistance.

Graphical abstract: Aptamer biosensor for label-free impedance spectroscopy detection of proteins based on recognition-induced switching of the surface charge

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Article information

DOI
https://doi.org/10.1039/B506571B
Article type
Communication
Submitted
11 May 2005
Accepted
14 Jun 2005
First published
12 Jul 2005

Chem. Commun., 2005, 4267-4269

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Aptamer biosensor for label-free impedance spectroscopy detection of proteins based on recognition-induced switching of the surface charge

M. C. Rodriguez, A. Kawde and J. Wang, Chem. Commun., 2005, 4267 DOI: 10.1039/B506571B

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