Issue 11, 2005
From the journal:

Chemical Communications

Selective guanine oxidation by UVB-irradiation in telomeric DNA

Kiyohiko Kawai,*a   Mamoru Fujitsukaa  and  Tetsuro Majima*b  

* Corresponding authors

a The Institute of Scientific and Industrial Research (SANKEN), Osaka University, Address Mihogaoka 8-1, Ibaraki, Japan
E-mail: kiyohiko@sanken.osaka-u.ac.jp
Fax: +81 6 6879 8499
Tel: +81 6 6879 8496

b The Institute of Scientific and Industrial Research (SANKEN), Osaka University, Address Mihogaoka 8-1, Ibaraki, Japan
E-mail: majima@sanken.osaka-u.ac.jp
Fax: +81 6 6879 8499
Tel: +81 6 6879 8495

Abstract

The combination of the transient absorption measurement and DNA damage quantification by HPLC clearly demonstrated the preferential excitation of guanine and its decomposition in quadruplex DNA by UVB-irradiation.

Graphical abstract: Selective guanine oxidation by UVB-irradiation in telomeric DNA

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Article information

DOI
https://doi.org/10.1039/B418000C
Article type
Communication
Submitted
30 Nov 2004
Accepted
23 Dec 2004
First published
21 Jan 2005

Chem. Commun., 2005, 1476-1477

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Selective guanine oxidation by UVB-irradiation in telomeric DNA

K. Kawai, M. Fujitsuka and T. Majima, Chem. Commun., 2005, 1476 DOI: 10.1039/B418000C

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