Issue 12, 2005
From the journal:

Chemical Communications

Synthesis of urea oligomers and their antibacterial activity†

Haizhong Tang,a   Robert J. Doerksen*b  and  Gregory N. Tew*a  

* Corresponding authors

a Department of Polymer Science and Engineering, University of Massachusetts, 120 Governors Drive, Amherst, USA
E-mail: tew@mail.pse.umass.edu
Fax: +01 413 545 0082

b Department of Medicinal Chemistry, University of Mississippi, University, MS 38677-1848, USA
E-mail: rjd@olemiss.edu

Abstract

Facially amphiphilic urea oligomers were successfully prepared in a one-pot reaction by carbonyl diimidazole (CDI) coupling and showed greater antibacterial activity against both Gram-negative Escherichia coli and Gram-positive Bacillus subtilis than MSI-78.

Graphical abstract: Synthesis of urea oligomers and their antibacterial activity

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Article information

DOI
https://doi.org/10.1039/B413679A
Article type
Communication
Submitted
07 Sep 2004
Accepted
13 Dec 2004
First published
28 Jan 2005

Chem. Commun., 2005, 1537-1539

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Synthesis of urea oligomers and their antibacterial activity

H. Tang, R. J. Doerksen and G. N. Tew, Chem. Commun., 2005, 1537 DOI: 10.1039/B413679A

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