Issue 15, 2004

Facile synthesis of membrane-embedded peptides utilizing lipid bilayer-assisted chemical ligation

Abstract

Lipid bilayer-assisted chemical ligation between thiolester and N-terminal cysteine peptides has been developed with successful application to the synthesis of membrane protein segments possessing both two transmembrane and one extracellular regions.

Graphical abstract: Facile synthesis of membrane-embedded peptides utilizing lipid bilayer-assisted chemical ligation

Supplementary files

Article information

Article type
Communication
Submitted
17 Mar 2004
Accepted
28 May 2004
First published
28 Jun 2004

Chem. Commun., 2004, 1722-1723

Facile synthesis of membrane-embedded peptides utilizing lipid bilayer-assisted chemical ligation

A. Otaka, S. Ueda, K. Tomita, Y. Yano, H. Tamamura, K. Matsuzaki and N. Fujii, Chem. Commun., 2004, 1722 DOI: 10.1039/B404008B

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