Issue 21, 2003
From the journal:

Chemical Communications

The effect of ruthenium(iii) chloride on the formation of protonated parent ions in electrospray mass spectrometry

Christian B. W. Stark,ab   Norberto P. Lopes,ac   Tatiana Fonsecaa  and  Paul J. Gates*a  

* Corresponding authors

a University of Cambridge, Department of Chemistry, Lensfield Road, Cambridge, UK
E-mail: pjg1002@cam.ac.uk
Fax: +44 (0) 1223 336362

b Institut Für Chemie – Organische Chemie, Freie Universität Berlin, Berlin, Germany

c Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Via do Café S/N, CEP 14.040-903, Ribeirão Preto-SP, Brazil

Abstract

We report the use of RuCl3 as an “alkali metal sponge”. This is a general and highly efficient method for generating protonated parent ions for a variety of compounds that usually do not show this ion in electrospray mass spectrometry. This technique is demonstrated to be highly useful in “cleaning up” spectra from multiply metallated ions, thereby substantially improving the signal-to-noise ratio.

Graphical abstract: The effect of ruthenium(iii) chloride on the formation of protonated parent ions in electrospray mass spectrometry

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/B309913J
Article type
Communication
Submitted
16 Aug 2003
Accepted
23 Sep 2003
First published
06 Oct 2003

Chem. Commun., 2003, 2732-2733

Permissions

Request permissions

The effect of ruthenium(III) chloride on the formation of protonated parent ions in electrospray mass spectrometry

C. B. W. Stark, N. P. Lopes, T. Fonseca and P. J. Gates, Chem. Commun., 2003, 2732 DOI: 10.1039/B309913J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements