Issue 15, 2003
From the journal:

Chemical Communications

The ion gating effect: using a change in flexibility to allow label free electrochemical detection of DNA hybridisation†

J. Justin Gooding,*a   Alison Chou,a   Freya J. Mearns,a   Elicia (Leh-See) Wonga  and  Kellie L. Jerichoa  

* Corresponding authors

a School of Chemical Sciences, The University of New South Wales, Sydney, NSW 2052, Australia
E-mail: justin.gooding@unsw.edu.au
Fax: +61-2-9385 6141
Tel: +61-2-9385 5384

Abstract

A label free electrochemical method of detecting DNA hybridisation is presented based on the change in flexibility between a single strand of DNA and a duplex causing an ion-gating effect where hybridisation opens up the electrode to access of ions.

Graphical abstract: The ion gating effect: using a change in flexibility to allow label free electrochemical detection of DNA hybridisation

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Article information

DOI
https://doi.org/10.1039/B305798B
Article type
Communication
Submitted
22 May 2003
Accepted
16 Jun 2003
First published
01 Jul 2003

Chem. Commun., 2003, 1938-1939

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The ion gating effect: using a change in flexibility to allow label free electrochemical detection of DNA hybridisation

J. J. Gooding, A. Chou, F. J. Mearns, E. (. Wong and K. L. Jericho, Chem. Commun., 2003, 1938 DOI: 10.1039/B305798B

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