Issue 22, 1998

Asymmetric Baylis–Hillman reactions: catalysis using a chiral pyrrolizidine base

Abstract

A novel chiral pyrrolizidine base 5 derived from L-proline promotes the Baylis–Hillman reaction of ethyl and methyl vinyl ketones with electron deficient aromatic aldehydes with moderate levels of enantiomeric excess.

Article information

Article type
Paper

Chem. Commun., 1998, 2533-2534

Asymmetric Baylis–Hillman reactions: catalysis using a chiral pyrrolizidine base

A. G. M. Barrett, A. S. Cook and A. Kamimura, Chem. Commun., 1998, 2533 DOI: 10.1039/A806115G

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