Two-step phosphorus-mediated substitution of hydroxy groups in selected primary alcohols for fluorinated alkyl or aryl substituents: the molecular structure of 1,1-bis(fluorosulfonyl)-1-fluoro-2-phenylethane

Abstract

In an Arbuzov type reaction, amido phosphites (Et₂N)₂- PORand a broad range of halofluoro organic halides (X = Cl, Br) formed the corresponding alkylated derivatives R¹–R² [R¹ = Bn, R² = C(SO₂F)₃, CCl₂F, CCl₂CF₃, CBr₂F, C(CF₃)₃, C₆F₅; R¹ = Et, CH₂CF₃, Me, R² = CCl₂CF₃], whereas with FC(SO₂F)₃ and loss of SO₂, BnCF(SO₂F)₂ was obtained, as shown by X-ray crystallography.