Issue 23, 1996

Remote 1,5-induction and steric approach control in Horner–Wadsworth–Emmons reactions. The stereoselective construction of trisubstituted, exocyclic double bonds from unsymmetric cyclic ketones

Abstract

The stereoselective formation of exocyclic α,β-unsaturated ester 8b from cyclic ketone 4 has been accomplished (E/Z= 9:1).

Article information

Article type
Paper

Chem. Commun., 1996, 2637-2638

Remote 1,5-induction and steric approach control in Horner–Wadsworth–Emmons reactions. The stereoselective construction of trisubstituted, exocyclic double bonds from unsymmetric cyclic ketones

T. F. J. Lampe and H. M. R. Hoffmann, Chem. Commun., 1996, 2637 DOI: 10.1039/CC9960002637

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