Jump to main content
Jump to site search

Issue 20, 1996
Previous Article Next Article

Enantioselective dioxygenase-catalysed formation and thermal racemisation of chiral thiophene sulfoxides

Abstract

Substituted chiral thiophene 1-oxides and their cycloadducts of variable enantiopurity have been isolated as products of dioxygenase-catalysed sulfoxidation of the corresponding thiophenes using intact cells of Pseudomonas putida; thermal racemization (ΔG= 25.1 kcal mol–1) of the enantiopure metabolite (1R)-2-methylbenzo[b]thiophene 1-oxide has been observed.

Back to tab navigation

Article type: Paper
DOI: 10.1039/CC9960002363
Citation: Chem. Commun., 1996,0, 2363-2364
  •   Request permissions

    Enantioselective dioxygenase-catalysed formation and thermal racemisation of chiral thiophene sulfoxides

    D. R. Boyd, N. D. Sharma, S. A. Haughey, J. F. Malone, B. T. McMurray, G. N. Sheldrake, C. C. R. Allen and H. Dalton, Chem. Commun., 1996, 0, 2363
    DOI: 10.1039/CC9960002363

Search articles by author

Spotlight

Advertisements