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Issue 3, 1996
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Aliphatic vs. aromatric C–H bond activation of phenylcyclohexane catalysed by cytochrome P450cam

Abstract

Catalytic hydroxylation of phenylcyclohexane 1 by wild-type and the Y96A and Y96F mutant forms of cytochrome P450cam occurs only at the 3- and 4-positions on the cyclohexane ring, giving cis-3-phenylcyclohexanol 2, cis-4-phenylcyclohexanol 3 and trans-4-phenylcyclohexanol 4.

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Article type: Paper
DOI: 10.1039/CC9960000357
Citation: Chem. Commun., 1996, 357-358
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    Aliphatic vs. aromatric C–H bond activation of phenylcyclohexane catalysed by cytochrome P450cam

    P. A. England, D. A. Rouch, A. C. G. Westlake, S. G. Bell, D. P. Nickerson, M. Webberley, S. L. Flitsch and L. Wong, Chem. Commun., 1996, 357
    DOI: 10.1039/CC9960000357

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