Molybdenum-mediated synthesis of isoxazole compounds through a nitrosyl insertion into a π-allyl ligand

Abstract

The syntheses of compounds of the type CpMo(CO)₂[η³-anti-1-CH₂CH(OH)R-syn-3-R′CH₂–C₃H₃] are described; their reactions with excess nitrosonium tetrafluoroborate produce 3-(1′-R′CH₂CHCH)-5-R-isoxazole, which involves a remarkable nitrosyl insertion into the π-allyl ligand as the key step.