Issue 17, 1991

Lipase catalysed regio- and enantio-selective hydrolysis: molecular recognition phenomenon and synthesis of (R)-dimorphecolic acid

Abstract

Molecular recognition has been observed in hydrolysis of racemic esters of (E)-9-acetoxy-11-bromoundec-10-enoic acid by a lipase of Candida cylindracea(E.C. 3.1.1.3) where optically active (R-(E)-9-acetoxy-11-bromoundec-10-enoic acid [enantiomeric excess (e.e.) > 99%] was obtained which was used in synthesis of (R)-dimorphecolic acid.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1991, 1197-1198

Lipase catalysed regio- and enantio-selective hydrolysis: molecular recognition phenomenon and synthesis of (R)-dimorphecolic acid

U. T. Bhalerao, L. Dasaradhi, P. Neelakantan and N. W. Fadnavis, J. Chem. Soc., Chem. Commun., 1991, 1197 DOI: 10.1039/C39910001197

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