Issue 17, 1991

Microbial hydroxylation of a dihydroartemisinin derivative

Abstract

The fungus Beauveria sulfurescens has been employed to convert the 14-methyl group of the phenylcarbamoyl of dihydroartemisinin to the corresponding 14-hydroxymethyl derivative; the structure of the product was established by mass and 2D NMR spectroscopy.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1991, 1176-1177

Microbial hydroxylation of a dihydroartemisinin derivative

Y. Hu, R. J. Highet, D. Marion and H. Ziffer, J. Chem. Soc., Chem. Commun., 1991, 1176 DOI: 10.1039/C39910001176

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