A concise enantioselective route to (–)-kainic acid from (S)-2-(benzyloxymethyl)oxirane
Abstract
A concise enantioselective route to (–)-kainic acid (1) from (S)-2-(benzyloxymethyl)oxirane (2) has been established by enantio- and diastereo-selective intramolecular 1,3-dipolar cyclization.