Issue 22, 1983

Penicillin biosynthesis. Dual pathways from a modified substrate

Abstract

Preparations of the enzyme isopenicillin N synthetase from Cephalosporium acremonium convert the modified substrate (L-α-amino-δ-adipyl)-L-cysteinyl-D-(α-aminobutyrate) into both penam and cepham products, which have been isolated and their structures established.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1983, 1317-1319

Penicillin biosynthesis. Dual pathways from a modified substrate

J. E. Baldwin, E. P. Abraham, R. M. Adlington, B. Chakravarti, A. E. Derome, J. A. Murphy, L. D. Field, N. B. Green, H. Ting and J. J. Usher, J. Chem. Soc., Chem. Commun., 1983, 1317 DOI: 10.1039/C39830001317

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements