1H n.m.r. studies of the orientation of some aromatic compounds by amphiphilic molecules and its relationship to regioselectivity in substitution

Abstract

¹ H N.m.r. spectroscopy of mono- and disubstituted phenols and their ethers micellar solutions of anionic and cationic detergents reveals non-uniform upfield shifts of the different protons in the solubilisate; these shifts can be rationalised in terms of a preferred average orientation of the solubilisate in the micelle.