The β-elimination of the 11-acetoxy-grouping of the aldehyde (2) by ready anion formation at C-12 gives the conjugated aldehyde (3); catalytic hydrogenation of (3), followed by alkylation under equilibrating conditions, allows access to novel prostaglandins, which are isomeric with PGF2α and PGE2.
P. Crabbé, A. Cervantes and M. C. Meana, J. Chem. Soc., Chem. Commun., 1973, 119 DOI: 10.1039/C39730000119
To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.
If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.
If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.
Read more about how to correctly acknowledge RSC content.
Please wait while we load your content...