Issue 8, 2016
From the journal:

Biomaterials Science

Reversing adhesion with light: a general method for functionalized bead release from cells†

Alexis Goulet-Hanssens, ORCID logo ‡ab   Margaret H. Magdesian,bcd   G. Monserratt Lopez-Ayon,bd   Peter Grutterbd  and  Christopher J. Barrett*ab  

* Corresponding authors

a Department of Chemistry, McGill University, 801 Sherbrooke St. West, Montreal, Canada
E-mail: christopher.barrett@mcgill.ca
Fax: +1 514 398 3797
Tel: +1 514 398 6919

b Program in NeuroEngineering, McGill University, Montreal, Canada

c ANANDA, Advanced Nano Design Applications, Montreal, Canada

d Department of Physics, McGill University, Montreal, Canada

Abstract

Coated beads retain great importance in the study of cell adhesion and intracellular communication; we present a generally applicable method permitting spatiotemporal control of bead adhesion from cells. Herein we demonstrate in vitro release of a poly-D-lysine (PDL) layer from anionic polystyrene beads, allowing complete bead release from rat cortical neurons post-adhesion.

Graphical abstract: Reversing adhesion with light: a general method for functionalized bead release from cells

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Article information

DOI
https://doi.org/10.1039/C6BM00168H
Article type
Communication
Submitted
08 Mar 2016
Accepted
01 May 2016
First published
11 May 2016

Biomater. Sci., 2016,4, 1193-1196

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Reversing adhesion with light: a general method for functionalized bead release from cells

A. Goulet-Hanssens, M. H. Magdesian, G. M. Lopez-Ayon, P. Grutter and C. J. Barrett, Biomater. Sci., 2016, 4, 1193 DOI: 10.1039/C6BM00168H

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