A novel fluorescent probe based on ESIPT and AIE processes for the detection of hydrogen peroxide and glucose and its application in nasopharyngeal carcinoma imaging

Abstract

A novel fluorescent probe HPQB based on ESIPT and AIE was developed for the detection of H₂O₂ and glucose. HPQB was found with large Stokes shift (167 nm) characters. Probe HPQB exhibited high selectivity and excellent sensitivity for H₂O₂ and glucose. Moreover, HPQB was also employed as a fluorescent probe for imaging H₂O₂ in nasopharyngeal carcinoma (NPC) cells.