Enzyme free glucose sensor exploiting a poly (dimethylaniline) grafted sulfonated ionomer-copper nanocomposite

Abstract

A new enzyme free glucose biosensor was fabricated based on poly(N,N′-dimethylaniline), sulfonated poly(ether ether ketone) and Cu(0) nanoparticles. The morphology and structure of the nanocomposites were characterized by X-ray diffraction (XRD) and scanning electron microscope (SEM) and was observed to be like nanoflowers. Amperometric and cyclic voltammetric methods were used to evaluate the performance of the sensor towards glucose. This enzyme free sensor showed synergistic electrocatalytic activity for glucose oxidation in 0.1 M KOH. The developed sensor displays linear range (0.5–5 mM) and sensitivity (19.3 μA mM⁻¹) with 0.1 μM (S/N = 3) detection limit. Also, modified GCE exhibited high reproducibility, long-term stability, good mechanical and chemical stabilities. Interferences of uric acid (UA) and ascorbic acid (AA) were completely avoided. Good analytical performance, low cost and straightforward preparation methodology suggested electrode as a promising material for effective glucose sensors.