Issue 12, 2018

Design of a wearable device for real-time screening of urinary tract infection and kidney disease based on smartphone

Abstract

In this study, we developed a novel wearable and low-cost device for qualitative screening of glucose (GLU), leukocytes (LEU), and nitrite (NIT) and for semi-quantitative analysis of blood (BLD) and proteins (PRO) in the urine samples. The device can be attached to a diaper, and the results can be read by an app. The main functions of the device can be divided into sample collection, valve closing, and pad saturation; the recorded times for valve closing and pad saturation at four corners and pad saturation at the central parts are pseudo-medians (Hodges–Lehmann estimator) of 3.55 (95% WCI, 3.45–3.72), 6.5 (95% WCI, 6–7), and 6 (95% WCI, 5.5–6.5) minutes, respectively. The RGB values in the reagent pads remain stable from 20 min to 480 min, which satisfies the requirement of regular diaper-wearing time. Pre-diagnostic results indicate high accuracy with good accuracy for the app recognition of five biomarkers in the urine samples, which makes it a promising tool for screening diseases, especially for the elderly healthcare.

Graphical abstract: Design of a wearable device for real-time screening of urinary tract infection and kidney disease based on smartphone

Supplementary files

Article information

Article type
Paper
Submitted
26 Jan 2018
Accepted
15 Apr 2018
First published
26 Apr 2018

Analyst, 2018,143, 2812-2818

Design of a wearable device for real-time screening of urinary tract infection and kidney disease based on smartphone

J. Zhou and T. Dong, Analyst, 2018, 143, 2812 DOI: 10.1039/C8AN00157J

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