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Issue 23, 2013
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A novel and photostable pH probe for selectively staining nuclei in living cells

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Abstract

A novel pH probe based on hemi-cyanine was synthesized, which displays extremely large Stokes shift (122 nm) and good photostability. The probe responds to basic pH (pKa 8.32) with a colorimetric and fluorescence turn-on signal. Interestingly, the probe has good cell membrane permeability and could selectively stain nuclei in living cells.

Graphical abstract: A novel and photostable pH probe for selectively staining nuclei in living cells

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Publication details

The article was received on 02 Sep 2013, accepted on 02 Oct 2013 and first published on 03 Oct 2013


Article type: Communication
DOI: 10.1039/C3AN01655B
Citation: Analyst, 2013,138, 7083-7086
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    A novel and photostable pH probe for selectively staining nuclei in living cells

    L. Zeng, N. Fan, J. Zha, X. Hu, B. Fu, C. Qin and L. Wang, Analyst, 2013, 138, 7083
    DOI: 10.1039/C3AN01655B

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