Issue 7, 2012
From the journal:

Analyst

A molecular light switch Ru complex and quantum dots for the label-free, aptamer-based detection of thrombin†

Wenliang Sun,a   Tianming Yao*a  and  Shuo Shi*a  

* Corresponding authors

a Department of Chemistry, Tongji University, Shanghai 200092, China
E-mail: tmyao@tongji.edu.cn, shishuo@tongji.edu.cn
Fax: +021 65983292
Tel: +021 65983292

Abstract

A simple, label-free method for the detection of thrombin has been developed based on the conformational transition of aptamer in the presence of the target by using a molecular light switch, Ru polypyridine complex, and quantum dots as novel fluorescence probes in aqueous solution.

Graphical abstract: A molecular light switch Ru complex and quantum dots for the label-free, aptamer-based detection of thrombin

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Article information

DOI
https://doi.org/10.1039/C2AN16181H
Article type
Communication
Submitted
01 Dec 2011
Accepted
04 Feb 2012
First published
21 Feb 2012

Analyst, 2012,137, 1550-1552

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A molecular light switch Ru complex and quantum dots for the label-free, aptamer-based detection of thrombin

W. Sun, T. Yao and S. Shi, Analyst, 2012, 137, 1550 DOI: 10.1039/C2AN16181H

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