Issue 12, 2010

Noninvasive biochemical monitoring of physiological stress by Fourier transform infrared saliva spectroscopy

Abstract

Physical stress affects the immune system, activates the sympathetic (SNS) and parasympathetic (PNS) subsytems of autonomic nervous system (ANS), and increases the activity of the hypothalamic-pituitary-adrenal axis (HPA). The specific response of the major regulatory systems depends on the human functional state. Saliva is a unique diagnostic fluid, the composition of which immediately reflects the SNS, PNS, HPA and immune system response to stress. A new method of saliva biomarker determination by Attenuated Total Reflection Fourier-Transform Infrared (ATR FTIR) spectroscopy has been developed to monitor the exercise induced metabolic changes in saliva from male endurance athletes. The method has been tested using a group of professional athletes by analysing saliva samples collected before and after the exercise, and the saliva composition monitoring by ATR FTIR spectroscopy was shown to be suitable for real-time checking of response to stress.

Graphical abstract: Noninvasive biochemical monitoring of physiological stress by Fourier transform infrared saliva spectroscopy

Supplementary files

Article information

Article type
Paper
Submitted
16 Jul 2010
Accepted
29 Sep 2010
First published
18 Oct 2010

Analyst, 2010,135, 3183-3192

Noninvasive biochemical monitoring of physiological stress by Fourier transform infrared saliva spectroscopy

S. Khaustova, M. Shkurnikov, E. Tonevitsky, V. Artyushenko and A. Tonevitsky, Analyst, 2010, 135, 3183 DOI: 10.1039/C0AN00529K

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