Issue 10, 2009
From the journal:

Analyst

A photoluminescent nanocrystal-based signaling protocol highly sensitive to nerve agents and highly toxic organophosphate pesticides†

Tao Yu,a   Jiang-Shan Shen,a   Hai-Hong Bai,b   Lei Guo,b   Ji-Jun Tang,b   Yun-Bao Jiang*a  and  Jian-Wei Xie*b  

* Corresponding authors

a Department of Chemistry and The MOE Key Laboratory of Analytical Sciences, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, China
E-mail: ybjiang@xmu.edu.cn
Fax: +86 592 2185662
Tel: +86 592 2185662

b Beijing Institute of Pharmacology and Toxicology, Beijing, China
E-mail: xiejw@bmi.ac.cn
Fax: + 86 10 68225893
Tel: + 86 10 68225893

Abstract

A photoluminescent II–VI group semiconductor nanocrystal (NC)-based signaling platform composed of thioglycolic acid capped CdS NCs and acetylcholinesterase-acetylthiocholine enzyme catalytic reaction system was developed that was shown to be highly sensitive to nerve agents and toxic organophosphate pesticides with detection limits down to sub-nM levels. This new sensing protocol does not require troublesome conjugation of biomacromolecules onto the surface of NCs.

Graphical abstract: A photoluminescent nanocrystal-based signaling protocol highly sensitive to nerve agents and highly toxic organophosphate pesticides

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Article information

DOI
https://doi.org/10.1039/B915159C
Article type
Paper
Submitted
24 Jul 2009
Accepted
10 Aug 2009
First published
24 Aug 2009

Analyst, 2009,134, 2153-2157

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A photoluminescent nanocrystal-based signaling protocol highly sensitive to nerve agents and highly toxic organophosphate pesticides

T. Yu, J. Shen, H. Bai, L. Guo, J. Tang, Y. Jiang and J. Xie, Analyst, 2009, 134, 2153 DOI: 10.1039/B915159C

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