Issue 5, 2009
From the journal:

Analyst

Quantitative SERRS immunoassay for the detection of human PSA†

Ross Stevenson,a   Andrew Ingram,a   Hing Leung,b   Donald C. McMillanb  and  Duncan Graham*a  

* Corresponding authors

a Centre for Molecular Nanometrology, WestCHEM, Department of Pure and Applied Chemistry, University of Strathclyde, Glasgow, UK
E-mail: duncan.graham@strath.ac.uk

b Division of Cancer Sciences and Molecular Pathology, University of Glasgow, Glasgow, UK

Abstract

We report the first use of a commonly used ELISA colorimetric substrate as a SERRS marker and show how it can be used for the detection of pg ml−1 levels of human prostate specific antigen (PSA) in clinical samples. The technique is amenable over a wide range of concentrations and lends itself to future multiplexing analysis.

Graphical abstract: Quantitative SERRS immunoassay for the detection of human PSA

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Article information

DOI
https://doi.org/10.1039/B902174D
Article type
Communication
Submitted
03 Feb 2009
Accepted
06 Mar 2009
First published
17 Mar 2009

Analyst, 2009,134, 842-844

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Quantitative SERRS immunoassay for the detection of human PSA

R. Stevenson, A. Ingram, H. Leung, D. C. McMillan and D. Graham, Analyst, 2009, 134, 842 DOI: 10.1039/B902174D

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