Issue 10, 2008
From the journal:

Analyst

Towards quantitatively reproducible substrates for SERS†

Roger M. Jarvis,*a   Helen E. Johnson,b   Emma Olembe,c   Arunkumar Panneerselvam,c   Mohammad A. Malik,c   Mohammad Afzaal,c   Paul O'Brien*c  and  Royston Goodacrea  

* Corresponding authors

a School of Chemistry, Manchester Interdisciplinary Biocentre, University of Manchester, 131 Princess Street, Manchester, UK
E-mail: roger.jarvis@manchester.ac.uk

b Faculty of Life Sciences, University of Manchester, Oxford Road, Manchester, UK

c School of Chemistry, University of Manchester, Brunswick Street, Manchester, UK
E-mail: paul.obrien@manchester.ac.uk

Abstract

There is a need for a method to facilitate the development of novel, reproducible colloidal surface-enhanced Raman scattering (SERS) substrates to encourage the use of SERS in applied studies. In this study we show for the first time that by using suitably designed SERS experiments in conjunction with multivariate analysis of variance (MANOVA), an objective assessment of colloidal SERS reproducibility can be made. This is demonstrated with the analyte cresyl violet, but could be extended to any analyte of interest for which reproducible SERS data are needed.

Graphical abstract: Towards quantitatively reproducible substrates for SERS

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Article information

DOI
https://doi.org/10.1039/B800340H
Article type
Paper
Submitted
09 Jan 2008
Accepted
11 Jun 2008
First published
25 Jul 2008

Analyst, 2008,133, 1449-1452

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Towards quantitatively reproducible substrates for SERS

R. M. Jarvis, H. E. Johnson, E. Olembe, A. Panneerselvam, M. A. Malik, M. Afzaal, P. O'Brien and R. Goodacre, Analyst, 2008, 133, 1449 DOI: 10.1039/B800340H

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