Ru(II)-catalyzed stereoselectivity C(7)-H α-fluoroalkenylation of indolines

Abstract

An efficient method of ruthenium(II)-catalyzed stereoselectivity C(7)−H α‑fluoroalkenylation of indolines is described. The protocol exhibited good functional group compatibility. The corresponding C7 fluoroalkenylated indolines can be obtained in moderate to excellent yields under mild and convenient conditions. Furthermore, two synthesized desired products show antibacterial activity against Staphylococcus aureus.

Supplementary files

Article information

Article type
Communication
Submitted
24 Sep 2025
Accepted
20 Oct 2025
First published
27 Oct 2025

Chem. Commun., 2025, Accepted Manuscript

Ru(II)-catalyzed stereoselectivity C(7)-H α-fluoroalkenylation of indolines

X. Liu, S. Xiao, H. Huang, L. Bai, W. Lai and G. Wu, Chem. Commun., 2025, Accepted Manuscript , DOI: 10.1039/D5CC05503B

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