Regioselective Postmodification of Aryl Sulfonyl Fluorides via Iridium(I)-Catalysed C-H Borylation

Abstract

Borylated aryl sulfonyl fluorides are versatile building blocks, demonstrating selective chemoselectivity in a variety of transformations. This work presents an efficient iridium-catalysed C–H borylation method for the regioselective synthesis of borylated aryl sulfonyl fluorides. The approach offers scalability to gram quantities and facilitates the conversion of both the boron and sulfonyl fluoride groups into diverse functional groups, enabling rapid access to key bioactive molecules.