From Spontaneous Ligand Evolution to High-Throughput Water-Based Synthesis: Scalable Access to CO2 Selective Mixed-Ligand Metal Organic Frameworks

Abstract

We report the discovery and synthesis of MOXI-214, a manganese-based metal-organic framework (MOF) with high selectivity for CO₂ adsorption. Oxalate ligands were generated by in situ ligand evolution from sodium ascorbate and incorporated into the framework under aqueous conditions. High-throughput experimentation enabled scalable production and the discovery of structural isomorphs.