Rhodium-catalyzed C–C bond alkenylation and arylation of α-branched N-sulfonyl amines

Abstract

This work demonstrates rhodium-catalyzed C–C bond cleavage of α-branched primary amines via β-carbon elimination. A pyridinyl group is employed to stabilize the rhodacycle intermediate, which subsequently undergoes either alkenylation with olefins or arylation with silane reagents. This novel protocol incorporates a broad range of both amines and coupling partners by utilizing cyclopentadienyl-type ligands.