Issue 15, 2024

Thermally-activated upconversion based on triplet fusion for deep red photoactivation of Ru(ii) complexes

Abstract

Expanding the anti-Stokes shift in triplet–triplet annihilation upconversion (TTA-UC) systems and harvesting light within the biological transparency window (700–900 nm) are of great importance for their biomedical applications. In this study, we have developed a TTA-UC system that converts deep red-light into blue photons using a highly endothermic sensitization pair, wherein the triplet energy level of the sensitizer is 0.19 eV below that of the acceptor. The thermally activated triplet energy transfer compensates the energy loss during intersystem crossing (ISC) of the sensitizer, achieving a 0.82 eV anti-Stokes shift upconversion with over 6% quantum yield. This TTA-UC system activates a Ru(II)-based photoactivated chemotherapeutic agent, causing DNA to bleach under 700 nm LED irradiation. These results demonstrate a feasible way to develop upconversion systems that operate within the biological transparency window, with potential applications in biological phototherapy.

Graphical abstract: Thermally-activated upconversion based on triplet fusion for deep red photoactivation of Ru(ii) complexes

Supplementary files

Article information

Article type
Paper
Submitted
31 Jan 2024
Accepted
12 Mar 2024
First published
13 Mar 2024

New J. Chem., 2024,48, 6886-6892

Thermally-activated upconversion based on triplet fusion for deep red photoactivation of Ru(II) complexes

P. Niu, X. Da, R. Hu, T. Yu, J. Chen, Q. Zhou, G. Luo, Y. Zeng and Y. Li, New J. Chem., 2024, 48, 6886 DOI: 10.1039/D4NJ00526K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements