From the journal:

Chemical Communications

Ligand-free 99mTc-polyurea dendrimer complexes: Nanoradiotheranostics targeted at ovarian cancer

Adriana Cruz,   Rita Pires,   Célia Fernandes,   António Rocha Paulo  and  Vasco D.B. Bonifácio  

Abstract

A folic acid-targeted polyurea (PURE) dendrimer was easily radiolabelled with Technetium-99m (99mTc-PUREG4-FA2) avoiding the use of additional ligands and bioconjugation chemistry. This straightforward strategy is enabled in PURE dendrimers due to their favourable surface terminal groups configuration, showing coordination capabilities and turning this biodendrimers attractive platforms for nanoradiotheranostics.

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Article information

DOI
https://doi.org/10.1039/D4CC00892H
Article type
Communication
Submitted
24 Feb 2024
Accepted
13 May 2024
First published
13 May 2024

Chem. Commun., 2024, Accepted Manuscript

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Ligand-free 99mTc-polyurea dendrimer complexes: Nanoradiotheranostics targeted at ovarian cancer

A. Cruz, R. Pires, C. Fernandes, A. R. Paulo and V. D.B. Bonifácio, Chem. Commun., 2024, Accepted Manuscript , DOI: 10.1039/D4CC00892H

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