Prenol and isoprenoids are common structural motifs in biological systems and possess diverse applications. An unprecedented direct catalytic prenylation of ketones using prenol is attained. This C–C bond formation reaction requires only a ruthenium pincer catalyst and a base, and H2O is the only byproduct.
R. V. Sankar, D. Manikpuri and C. Gunanathan, Org. Biomol. Chem., 2023, 21, 273 DOI: 10.1039/D2OB01882A
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