Issue 48, 2023
From the journal:

Chemical Communications

Dansyl-triazole-based fluorescent macrocycle for selective detection of nitro-antibiotic drugs and protein interaction†

Liya Thurakkal,a   Rakhi Mol K. M.a  and  Mintu Porel ORCID logo *ab  

* Corresponding authors

a Department of Chemistry, Indian Institute of Technology Palakkad, Kerala 678557, India
E-mail: mintu@iitpkd.ac.in

b Environmental Sciences and Sustainable Engineering Centre, Indian Institute of Technology Palakkad, Kerala 678557, India

Abstract

A novel dansyl-triazole-based fluorescent macrocycle with high Stokes shift and positive solvatochromism was developed. This is an excellent fluorescence sensor for selective detection of nitro-containing antibiotics and other nitro-heteroaromatics. Detection was possible in real samples/paper strips in submicromolar concentration. The interaction of the macrocycle with multiple proteins exhibited its bioactivity.

Graphical abstract: Dansyl-triazole-based fluorescent macrocycle for selective detection of nitro-antibiotic drugs and protein interaction

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Article information

DOI
https://doi.org/10.1039/D3CC01769A
Article type
Communication
Submitted
11 Apr 2023
Accepted
08 May 2023
First published
09 May 2023
This article is Open Access
Creative Commons BY-NC license

Chem. Commun., 2023,59, 7399-7402

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Dansyl-triazole-based fluorescent macrocycle for selective detection of nitro-antibiotic drugs and protein interaction

L. Thurakkal, R. Mol K. M. and M. Porel, Chem. Commun., 2023, 59, 7399 DOI: 10.1039/D3CC01769A

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