Facet-dependence of Fe3O4 for enhancing osteogenic differentiation of BMSCs

Xinlin Wei; Fei Wang; Jie Tao; Jian Mao

doi:10.1039/D3CC00703K

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Facet-dependence of Fe₃O₄ for enhancing osteogenic differentiation of BMSCs†

Xinlin Wei,‡^a Fei Wang,

‡^a Jie Tao*^b and Jian Mao

*^a

Author affiliations

* Corresponding authors

^a College of Materials Science and Engineering, Sichuan University, Chengdu 610065, China
E-mail: maojian@scu.edu.cn

^b Department of Stomatology, Daping Hospital, Army Medical University (The Third Military Medical University), Chongqing 400042, China
E-mail: taojietanker@sina.com

Abstract

Herein, the facet-dependence of Fe₃O₄ for enhancing osteogenic differentiation is demonstrated for the first time. Experimental results and density functional theory calculations reveal that Fe₃O₄ with exposed (4 [2 with combining macron] 2) facets has greater potential in inducing osteogenic differentiation of stem cells compared with that with exposed (400) facets. Moreover, the mechanisms underlying this phenomenon are revealed.

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Article information

DOI: https://doi.org/10.1039/D3CC00703K
Article type: Communication
Submitted: 15 Feb 2023
Accepted: 10 May 2023
First published: 16 May 2023

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Chem. Commun., 2023,59, 6742-6744

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Facet-dependence of Fe₃O₄ for enhancing osteogenic differentiation of BMSCs

X. Wei, F. Wang, J. Tao and J. Mao, Chem. Commun., 2023, 59, 6742 DOI: 10.1039/D3CC00703K

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