Near-infrared photothermally activated DNA nanotweezers for imaging ATP in living cells

Xiao-Qiong Li; Dan Luo; Juan Song; Yi-Lei Jia; Juan Song; Hong-Yuan Chen; Jing-Juan Xu

doi:10.1039/D2CC02791G

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Near-infrared photothermally activated DNA nanotweezers for imaging ATP in living cells†

Xiao-Qiong Li,^a Dan Luo,^a Juan Song,^a Yi-Lei Jia,^a Juan Song,*^a Hong-Yuan Chen^a and Jing-Juan Xu

*^a

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* Corresponding authors

^a State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, China
E-mail: juansong@nju.edu.cn, xujj@nju.edu.cn

Abstract

By assembling nanotweezers with ATP-splitting aptamers on gold nanorods (AuT123L), we constructed a near-infrared-activated ATP sensing device that could time-controllably image ATP levels in living cells. By replacing the aptamers on the nanotweezers, the nanoplatform can be applied to other important biomolecules, opening up more possibilities for the study of time controllable nanodevices.

This article is part of the themed collection: Sensors for Health

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Article information

DOI: https://doi.org/10.1039/D2CC02791G
Article type: Communication
Submitted: 17 May 2022
Accepted: 27 Jun 2022
First published: 28 Jun 2022

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Chem. Commun., 2022,58, 8210-8213

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Near-infrared photothermally activated DNA nanotweezers for imaging ATP in living cells

X. Li, D. Luo, J. Song, Y. Jia, J. Song, H. Chen and J. Xu, Chem. Commun., 2022, 58, 8210 DOI: 10.1039/D2CC02791G

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Chemical Communications

Near-infrared photothermally activated DNA nanotweezers for imaging ATP in living cells†

Abstract

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Near-infrared photothermally activated DNA nanotweezers for imaging ATP in living cells

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