Issue 46, 2022

MnO2–DNA nanomaterials toward the dual signal detection of P-aminophenol micropollutants

Abstract

P-Aminophenol (PAP), a potentially toxic and mutagenic compound, is widely distributed in water and soil and has serious side effects on human health. This study presents a convenient, sensitive, and effective dual-signal assay for the detection of PAP in the environment. Two-dimensional manganese dioxide (MnO2) nanosheets were used as the carrier and quencher for fluorophore-labelled DNA to form a dual-signal nanoprobe, MnO2–DNA. Based on a specific redox reaction between the MnO2 nanosheets and target PAP, the corresponding absorption intensity of the product and the fluorescence intensity were both “turn-on” and also exhibited excellent correlation with the concentration of PAP. This strategy not only remarkably simplifies the detection process but also improves the reliability of results due to the dual-signal response, which has promising applications in environmental, clinical, and industrial research fields.

Graphical abstract: MnO2–DNA nanomaterials toward the dual signal detection of P-aminophenol micropollutants

Supplementary files

Article information

Article type
Paper
Submitted
13 Sep 2022
Accepted
07 Nov 2022
First published
08 Nov 2022

Anal. Methods, 2022,14, 4867-4871

MnO2–DNA nanomaterials toward the dual signal detection of P-aminophenol micropollutants

X. Li, Z. Wang, Q. Zhang, D. Luo and J. J. Xie, Anal. Methods, 2022, 14, 4867 DOI: 10.1039/D2AY01484J

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