Issue 66, 2021

Sensitive imaging of tumors using a nitroreductase-activated fluorescence probe in the NIR-II window

Abstract

A nitroreductase (NTR)-activated NIR-II fluorescence probe for tumor imaging is reported. The probe can emit fluorescence in the range of 900–1300 nm, and target hypoxic tumors with NTR overexpression, thus allowing for accurate delineation of tumor margins through deep penetration.

Graphical abstract: Sensitive imaging of tumors using a nitroreductase-activated fluorescence probe in the NIR-II window

Supplementary files

Article information

Article type
Communication
Submitted
18 Jun 2021
Accepted
16 Jul 2021
First published
16 Jul 2021

Chem. Commun., 2021,57, 8174-8177

Sensitive imaging of tumors using a nitroreductase-activated fluorescence probe in the NIR-II window

X. Zhang, X. Li, W. Shi and H. Ma, Chem. Commun., 2021, 57, 8174 DOI: 10.1039/D1CC03232A

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