Issue 4, 2021

Real-time imaging of alkaline phosphatase activity of diabetes in mice via a near-infrared fluorescent probe

Abstract

A novel water-soluble near-infrared fluorescent probe named QX-P with simple synthesis is developed. QX-P has high sensitivity and selectivity to ALP. Moreover, the probe can not only visualize ALP activity in four cell lines, but also real-time image ALP activity during the diagnosis and treatment of diabetes in mice.

Graphical abstract: Real-time imaging of alkaline phosphatase activity of diabetes in mice via a near-infrared fluorescent probe

Supplementary files

Article information

Article type
Communication
Submitted
04 Nov 2020
Accepted
01 Dec 2020
First published
09 Dec 2020

Chem. Commun., 2021,57, 480-483

Real-time imaging of alkaline phosphatase activity of diabetes in mice via a near-infrared fluorescent probe

W. Wang, W. Jiang, H. Guo, Y. Li and C. Li, Chem. Commun., 2021, 57, 480 DOI: 10.1039/D0CC07292C

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