A convenient method for synthesis of terpyridines via a cooperative vinylogous anomeric based oxidation

Abstract

The presented study is the first report of the synthesis of terpyridines in the presence of a nanomagnetic catalyst instead of harmful reagents. Herein, Fe₃O₄@O₂PO₂(CH₂)₂NH₃⁺CF₃CO₂⁻ as a retrievable nanocatalyst with magnetic properties was applied for the multi-component reaction between acetylpyridine derivatives (2 or 3 or 4-isomer), aryl aldehydes and ammonium acetate under conventional heating conditions in the absence of any solvent. The derived terpyridines were obtained with acceptable yields and brief reaction times via a cooperative vinylogous anomeric based oxidation route. Fe₃O₄@O₂PO₂(CH₂)₂NH₃⁺CF₃CO₂⁻ showed a high capability for recovery and reuse in the mentioned reaction.