Issue 31, 2020, Issue in Progress

In(OTf)3-catalyzed intramolecular hydroarylation of α-phenylallyl β-ketosulfones – synthesis of sulfonyl 1-benzosuberones and 1-tetralones

Abstract

In(OTf)3-catalyzed intramolecular hydroarylation of α-phenylallyl β-ketosulfones provides sulfonyl 1-benzosuberones and 1-tetralones in moderate to good yields in refluxing (CH2Cl)2 under open-vessel and easy-operation reaction conditions. A plausible mechanism is proposed and discussed. This highly regioselective protocol provides an atom-economic ring-closure route.

Graphical abstract: In(OTf)3-catalyzed intramolecular hydroarylation of α-phenylallyl β-ketosulfones – synthesis of sulfonyl 1-benzosuberones and 1-tetralones

Supplementary files

Article information

Article type
Paper
Submitted
01 Mar 2020
Accepted
05 May 2020
First published
13 May 2020
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2020,10, 18231-18244

In(OTf)3-catalyzed intramolecular hydroarylation of α-phenylallyl β-ketosulfones – synthesis of sulfonyl 1-benzosuberones and 1-tetralones

M. Chang, K. Lai and Y. Chang, RSC Adv., 2020, 10, 18231 DOI: 10.1039/D0RA01962C

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