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Physico-chemical studies of resveratrol, methyl-jasmonate and cyclodextrin interactions: an approach to resveratrol bioproduction optimization

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Abstract

trans-Resveratrol (RSV) is a natural phenolic molecule of the stilbene family known for its anti-oxidant properties in the field of nutraceuticals and cosmetics. Its production by grapevine cell suspensions is induced by the addition to the culture medium of elicitor compounds, methyl jasmonate (MeJA) and cyclodextrins (CDs). Physico-chemical studies were performed to understand the mechanism of action of CDs on this bioproduction of RSV. Inclusion complexes of RSV in CDs were first observed and then interactions with MeJA were identified using various analytical techniques such as UV and nuclear magnetic resonance (NMR) spectroscopies, mass spectrometry (MS) and isothermal titration calorimetry (ITC).

Graphical abstract: Physico-chemical studies of resveratrol, methyl-jasmonate and cyclodextrin interactions: an approach to resveratrol bioproduction optimization

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Publication details

The article was received on 20 Oct 2017, accepted on 18 Dec 2017 and first published on 04 Jan 2018


Article type: Paper
DOI: 10.1039/C7RA11619E
Citation: RSC Adv., 2018,8, 1528-1538
  • Open access: Creative Commons BY license
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    Physico-chemical studies of resveratrol, methyl-jasmonate and cyclodextrin interactions: an approach to resveratrol bioproduction optimization

    E. Oliva, D. Mathiron, E. Bertaut, D. Landy, D. Cailleu, S. Pilard, C. Clément, E. Courot, V. Bonnet and F. Djedaïni-Pilard, RSC Adv., 2018, 8, 1528
    DOI: 10.1039/C7RA11619E

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