Jump to main content
Jump to site search


1,4-Refunctionalization of β-Diketones to γ-Keto Nitriles via C-C Single Bond Cleavage

Abstract

1,4-Refunctionalization of β-diketones to γ-keto nitriles was realized via Fe-catalyzed cascade radical process. The C-C single bond cleavage occurred at the less sterically hindered alkyl ketone side or at the side of β-diarylketones with electron-withdrawing group. The reaction mechanism was proposed under the ESI-MS analysis results.

Back to tab navigation

Supplementary files

Publication details

The article was received on 06 Jun 2018, accepted on 11 Jul 2018 and first published on 12 Jul 2018


Article type: Research Article
DOI: 10.1039/C8QO00556G
Citation: Org. Chem. Front., 2018, Accepted Manuscript
  •   Request permissions

    1,4-Refunctionalization of β-Diketones to γ-Keto Nitriles via C-C Single Bond Cleavage

    Q. Wu, Y. Li, C. Wang, J. Zhang, M. Huang, J. K. Kim and Y. Wu, Org. Chem. Front., 2018, Accepted Manuscript , DOI: 10.1039/C8QO00556G

Search articles by author

Spotlight

Advertisements