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Recent advances in the synthesis of azaphenalene alkaloids. First enantioselective approaches

Abstract

The azaphenalene alkaloids are biosynthesised and segregated by diverse insects of the Coccinellidae family (ladybirds) and are believed to play an important role in the defensive mechanism against their natural predators. The particular unique framework of these alkaloids, along with their potential in the field of biological pest control, has led to several research groups to develop synthetic sequences to prepare these compounds. The main purpose of the present review is providing an update of the more recent synthetic progress towards these alkaloids, including the pioneer enantioselective approaches to the chiral congeners.

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Publication details

The article was received on 19 Jun 2018, accepted on 02 Aug 2018 and first published on 03 Aug 2018


Article type: Review Article
DOI: 10.1039/C8OB01443D
Citation: Org. Biomol. Chem., 2018, Accepted Manuscript
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    Recent advances in the synthesis of azaphenalene alkaloids. First enantioselective approaches

    M. Figueredo, P. Bayón and S. Alujas-Burgos, Org. Biomol. Chem., 2018, Accepted Manuscript , DOI: 10.1039/C8OB01443D

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