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Issue 19, 2018
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Iodine-catalyzed oxidative annulation of 3-cyanoacetylindoles with benzylamines: facile access to 5-(3-indolyl)oxazoles

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Abstract

An iodine-catalyzed oxidative annulation of 3-cyanoacetylindoles with benzylamines has been developed. This reaction enables the convenient synthesis of a variety of 5-(3-indolyl)oxazoles under mild conditions with broad functional group compatibility.

Graphical abstract: Iodine-catalyzed oxidative annulation of 3-cyanoacetylindoles with benzylamines: facile access to 5-(3-indolyl)oxazoles

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Publication details

The article was received on 09 Apr 2018, accepted on 23 Apr 2018 and first published on 26 Apr 2018


Article type: Communication
DOI: 10.1039/C8OB00833G
Citation: Org. Biomol. Chem., 2018,16, 3572-3575
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    Iodine-catalyzed oxidative annulation of 3-cyanoacetylindoles with benzylamines: facile access to 5-(3-indolyl)oxazoles

    X. Liu, Y. Zhou, G. Chen, Z. Yang, Q. Li and P. Liu, Org. Biomol. Chem., 2018, 16, 3572
    DOI: 10.1039/C8OB00833G

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