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Issue 19, 2018
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In vivo and in vitro identification of Z-BOX C – a new bilirubin oxidation end product

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Abstract

A new bilirubin oxidation end product (BOX) was isolated and characterized. The formation of the so-called Z-BOX C proceeds from bilirubin via propentdyopents as intermediates. This BOX was detected in pathological human bile samples using liquid chromatography/mass spectrometry and has potential relevance for liver dysfunction and cerebral vasospasms.

Graphical abstract: In vivo and in vitro identification of Z-BOX C – a new bilirubin oxidation end product

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Publication details

The article was received on 19 Jan 2018, accepted on 01 Mar 2018 and first published on 01 Mar 2018


Article type: Communication
DOI: 10.1039/C8OB00164B
Citation: Org. Biomol. Chem., 2018,16, 3553-3555
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    In vivo and in vitro identification of Z-BOX C – a new bilirubin oxidation end product

    M. Ritter, S. Neupane, R. A. Seidel, C. Steinbeck and G. Pohnert, Org. Biomol. Chem., 2018, 16, 3553
    DOI: 10.1039/C8OB00164B

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