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Issue 23, 2018
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Aptamer-based multifunctional ligand-modified UCNPs for targeted PDT and bioimaging

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Abstract

We designed an aptamer-based multifunctional ligand which, upon conjugation to the surface of upconversion nanoparticles (UCNPs), could realize phase transfer, covalent photosensitizer (PS) loading, and cancer cell targeting in one simple step. The as-built PDT nanodrug is selectively internalized into cancer cells and it exhibits highly efficient and selective cytotoxicity.

Graphical abstract: Aptamer-based multifunctional ligand-modified UCNPs for targeted PDT and bioimaging

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Publication details

The article was received on 06 Feb 2018, accepted on 26 Apr 2018 and first published on 03 May 2018


Article type: Paper
DOI: 10.1039/C8NR01096J
Citation: Nanoscale, 2018,10, 10986-10990
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    Aptamer-based multifunctional ligand-modified UCNPs for targeted PDT and bioimaging

    W. Hou, Y. Liu, Y. Jiang, Y. Wu, C. Cui, Y. Wang, L. Zhang, I. Teng and W. Tan, Nanoscale, 2018, 10, 10986
    DOI: 10.1039/C8NR01096J

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