Issue 5, 2018

Adsorption and binding dynamics of graphene-supported phospholipid membranes using the QCM-D technique

Abstract

We report on the adsorption dynamics of phospholipid membranes on graphene-coated substrates using the quartz crystal microbalance with dissipation monitoring (QCM-D) technique. We compare the lipid vesicle interaction and membrane formation on gold and silicon dioxide QCM crystal surfaces with their graphene oxide (GO) and reduced (r)GO coated counterparts, and report on the different lipid structures obtained. We establish graphene derivative coatings as support surfaces with tuneable hydrophobicity for the formation of controllable lipid structures. One structure of interest formed is lipid monolayer membranes which were formed on rGO, which are otherwise challenging to produce. We also demonstrate and monitor biotin–avidin binding on such a membrane, which will then serve as a platform for a wide range of biosensing applications. The QCM-D technique could be extended to both fundamental studies and applications of other covalent and non-covalent interactions in 2-dimensional materials.

Graphical abstract: Adsorption and binding dynamics of graphene-supported phospholipid membranes using the QCM-D technique

Supplementary files

Article information

Article type
Paper
Submitted
31 Jul 2017
Accepted
16 Dec 2017
First published
03 Jan 2018

Nanoscale, 2018,10, 2555-2567

Adsorption and binding dynamics of graphene-supported phospholipid membranes using the QCM-D technique

D. Meléndrez, T. Jowitt, M. Iliut, A. F. Verre, S. Goodwin and A. Vijayaraghavan, Nanoscale, 2018, 10, 2555 DOI: 10.1039/C7NR05639G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements